Liver-on-a-chip Market by Type (Child Liver-on-a-chip and Adult Liver-on-a-chip), by Application (Drug Discovery, Toxicology Research and Others), End User (Pharmaceutical & Biotechnology Companies, Academic & Research Institutes and Others), Region, Global Industry Analysis, Market Size, Share, Growth, Trends, and Forecast 2023 to 2032

  • Publish Date: May, 2023
  • Report ID: 420254
  • Category: Healthcare
  • Pages: 237
$4700

The Liver-on-a-chip market is expected to grow from USD 52 million in 2022 to USD 379.84 million by 2032, at a CAGR of 22% during the forecast period 2023-2032.

Liver-on-a-chip is a micro-physiological system which mimics the function of the liver. The liver plays several vital roles in the body. But it is known as a part of the digestive tract. Liver-on-a-chip helps researchers understand and analyze how the liver processes drugs and other compounds. Many liver-on-a-chip systems are constructed using poly(dimethylsiloxane) (PDMS) with multiple channels and chambers depending upon precise design and aim.

The driving factors of the market growth are the rise in cases of liver diseases and technological advancements. However, lack of awareness and the high cost of the device will act as a restraining factor for the market. Collaboration and partnerships between various institutions, private and public organizations and pharma companies can help to develop the market and propel market growth over the forecast period.

This study delivers a comprehensive analysis of type, application, end user, and region. The type segment includes child liver-on-a-chip and adult liver-on-a-chip. The adult liver-on-a-chip segment held the largest market share in 2022. This is mainly due to rise in the geriatric population and more significant market for drugs developed for adults. The application segment includes drug discovery, toxicology research and others. The drug discovery segment held the largest market share in 2022. Liver-on-a-chip is utilized to check the efficacy and toxicity of the new drugs. This will help pace the drug development process and reduce the need for animals for drug testing. The end user segment includes pharmaceutical & biotechnology companies, academic & research institutes and others. The pharmaceutical & biotechnology companies segment held the largest market share in 2022. This is mainly because pharmaceutical & biotechnology companies can develop more safer & effective drugs for the patients. Also, it will allow them to analyze how the drug is working and how the body is responding towards it.

The market has been divided into North America, Europe, Asia-Pacific, Middle East & Africa, and South America. North America holds the largest market share due to the rising cases of liver diseases and the presence of a large number of pharmaceutical companies, government organizations and research institutions spending on the research and development of the Liver-on-a-chip devices. Europe is expected to grow at a significant market share due to the presence of strong healthcare infrastructure and demand for drug discovery and development technologies.

Some of the notable players in the market are Cherry Biotech SAS, CN Bio Innovations, Draper Laboratory, Else Else Kooi Laboratory, Emulate, Hesperos, Kirkstall, Micronit Microtechnologies B.V., Mimetas, Nortis, Tissuse and among others.

  • Global Liver-on-a-chip Market Analysis and Forecast, Type  
    • Child Liver-on-a-chip
    • Adult Liver-on-a-chip
  • Global Liver-on-a-chip Market Analysis and Forecast, Application
    • Drug Discovery
    • Toxicology Research
    • Others
  • Global Liver-on-a-chip Market Analysis and Forecast, End User
    • Pharmaceutical and Biotechnology Companies
    • Academic and Research Institutes
    • Others
  • Global Liver-on-a-chip Market Analysis and Forecast, Region
    • North America
      • U.S.
      • Canada
      • Mexico
    • Europe
      • Germany
      • France
      • Sweden
      • Netherland
      • U.K.
      • Italy
      • Spain
      • Turkey
      • Switzerland
      • Belgium
      • Rest Of Europe
    • Asia-Pacific
      • Japan
      • China
      • India
      • South Korea
      • Australia
      • Singapore
      • Malaysia
      • Thailand
      • Indonesia
      • Philippines
      • Rest Of APAC
    • South America
      • Brazil
      • Argentina
      • Peru
      • Colombia
      • Rest Of South America
    • Middle East And Africa
      •  UAE
      •  Saudi Arabia
      •  Egypt
      •  Nigeria
      •  South Africa
      • Rest Of MEA

Report Description:

  • The base year for the study has been considered 2022, historic year 2019 and 2021, the forecast period considered is from 2023 to 2032.
  • The study delivers a comprehensive analysis of global market for all segments and region.
  • The report offers in-depth analysis of driving factors, opportunities and restraints for gaining the key insight of the market. The report emphasizes on all the key trends that play a vital role in the enlargement of the market from 2023 to 2032.
  • Porter’s Five Forces model is used in order to recognize the competitive scenario in the market. This report incorporates the industry analysis which is focused on providing an extensive view of the market.
  • The study also includes attractiveness analysis of all segments and regions which are benchmarked based on their market size, growth rate and attractiveness in terms of present and future opportunist for understanding the future growth of the market.
  • The report provides company profile of the key players operating in the market and a comparative analysis based on their business overviews, product offering, segment market share, regional presence, business strategies, innovations, mergers & acquisitions, recent developments, joint venture, collaborations, partnerships, SWOT analysis, and key financial information.
  • The market estimates have been evaluated by considering the effect of different political, economic, social, technological and legal factors which are based on our extensive secondary research, primary research, and in-house databases.

1. Introduction
    1.1. Objectives of the Study
    1.2. Market Definition
    1.3. Research Scope
    1.4. Currency
    1.5. Key Target Audience
2. Research Methodology and Assumptions
3. Executive Summary
4. Premium Insights
    4.1. Porter’s Five Forces Analysis
    4.2. Value Chain Analysis
    4.3. Top Investment Pockets
          4.3.1. Market Attractiveness Analysis by Type
          4.3.2. Market Attractiveness Analysis by Application
          4.3.3. Market Attractiveness Analysis by End User
          4.3.4. Market Attractiveness Analysis by Region
    4.4. Industry Trends
5. Market Dynamics
    5.1. Market Evaluation
    5.2. Drivers
          5.2.1. Rise in cases of liver diseases
          5.2.2. Technological advancements
    5.3. Restraints
          5.3.1. Lack of awareness
          5.3.2. High cost of the device
    5.4. Opportunities
          5.4.1. Collaboration and partnerships between various institutions, private and public organizations and pharma companies
6. Global Liver-on-a-chip Market Analysis and Forecast, By Type
    6.1. Segment Overview
    6.2. Child Liver-on-a-chip
    6.3. Adult Liver-on-a-chip
7. Global Liver-on-a-chip Market Analysis and Forecast, By Application
    7.1. Segment Overview
    7.2. Drug Discovery
    7.3. Toxicology Research
    7.4. Others
8. Global Liver-on-a-chip Market Analysis and Forecast, By End User
    8.1. Segment Overview
    8.2. Pharmaceutical and Biotechnology Companies
    8.3. Academic and Research Institutes
    8.4. Others
9. Global Liver-on-a-chip Market Analysis and Forecast, By Regional Analysis
    9.1. Segment Overview
    9.2. North America
          9.2.1. U.S.
          9.2.2. Canada
          9.2.3. Mexico
    9.3. Europe
          9.3.1. Germany
          9.3.2. France
          9.3.3. U.K.
          9.3.4. Italy
          9.3.5. Spain
    9.4. Asia-Pacific
          9.4.1. Japan
          9.4.2. China
          9.4.3. India
    9.5. South America
          9.5.1. Brazil
    9.6. Middle East and Africa
          9.6.1. UAE
          9.6.2. South Africa
10. Global Liver-on-a-chip Market-Competitive Landscape
    10.1. Overview
    10.2. Market Share of Key Players in Global Liver-on-a-chip Market
          10.2.1. Global Company Market Share
          10.2.2. North America Company Market Share
          10.2.3. Europe Company Market Share
          10.2.4. APAC Company Market Share
    10.3. Competitive Situations and Trends
          10.3.1. Product Launches and Developments
          10.3.2. Partnerships, Collaborations, and Agreements
          10.3.3. Mergers & Acquisitions
          10.3.4. Expansions
11. Company Profiles
    11.1. Cherry Biotech SAS
          11.1.1. Business Overview
          11.1.2. Company Snapshot
          11.1.3. Company Market Share Analysis
          11.1.4. Company Product Portfolio
          11.1.5. Recent Developments
          11.1.6. SWOT Analysis
    11.2. CN Bio Innovations
          11.2.1. Business Overview
          11.2.2. Company Snapshot
          11.2.3. Company Market Share Analysis
          11.2.4. Company Product Portfolio
          11.2.5. Recent Developments
          11.2.6. SWOT Analysis
    11.3. Draper Laboratory
          11.3.1. Business Overview
          11.3.2. Company Snapshot
          11.3.3. Company Market Share Analysis
          11.3.4. Company Product Portfolio
          11.3.5. Recent Developments
          11.3.6. SWOT Analysis
    11.4. Else Else Kooi Laboratory
          11.4.1. Business Overview
          11.4.2. Company Snapshot
          11.4.3. Company Market Share Analysis
          11.4.4. Company Product Portfolio
          11.4.5. Recent Developments
          11.4.6. SWOT Analysis
    11.5. Emulate
          11.5.1. Business Overview
          11.5.2. Company Snapshot
          11.5.3. Company Market Share Analysis
          11.5.4. Company Product Portfolio
          11.5.5. Recent Developments
          11.5.6. SWOT Analysis
    11.6. Emulate
          11.6.1. Business Overview
          11.6.2. Company Snapshot
          11.6.3. Company Market Share Analysis
          11.6.4. Company Product Portfolio
          11.6.5. Recent Developments
          11.6.6. SWOT Analysis
    11.7. Kirkstall
          11.7.1. Business Overview
          11.7.2. Company Snapshot
          11.7.3. Company Market Share Analysis
          11.7.4. Company Product Portfolio
          11.7.5. Recent Developments
          11.7.6. SWOT Analysis
    11.8. Micronit Microtechnologies B.V.
          11.8.1. Business Overview
          11.8.2. Company Snapshot
          11.8.3. Company Market Share Analysis
          11.8.4. Company Product Portfolio
          11.8.5. Recent Developments
          11.8.6. SWOT Analysis
    11.9. Mimetas
          11.9.1. Business Overview
          11.9.2. Company Snapshot
          11.9.3. Company Market Share Analysis
          11.9.4. Company Product Portfolio
          11.9.5. Recent Developments
          11.9.6. SWOT Analysis
    11.10. Nortis
          11.10.1. Business Overview
          11.10.2. Company Snapshot
          11.10.3. Company Market Share Analysis
          11.10.4. Company Product Portfolio
          11.10.5. Recent Developments
          11.10.6. SWOT Analysis
    11.11. Tissuse
          11.11.1. Business Overview
          11.11.2. Company Snapshot
          11.11.3. Company Market Share Analysis
          11.11.4. Company Product Portfolio
          11.11.5. Recent Developments
          11.11.6. SWOT Analysis

List of Table

1. Global Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

2. Global Child Liver-on-a-chip, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million) 

3. Global Adult Liver-on-a-chip, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million) 

4. Global Liver-on-a-chip Market, By Application, 2019-2032 (USD Million)

5. Global Drug Discovery, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million)

6. Global Toxicology Research, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million)

7. Global Others, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million)

8. Global Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

9. Global Pharmaceutical and Biotechnology Companies, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million)

10. Global Academic and Research Institutes, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million)

11. Global Others, Liver-on-a-chip Market, By Region, 2019-2032 (USD Million)

12. North America Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

13. North America Liver-on-a-chip Market, By Application, 2019-2032 (USD Million)

14. North America Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

15. U.S. Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

16. U.S. Liver-on-a-chip Market, By Application, 2019-2032 (USD Million)

17. U.S. Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

18. Canada Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

19. Canada Liver-on-a-chip Market, By Application, 2019-2032 (USD Million)

20. Canada Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

21. Mexico Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

22. Mexico Liver-on-a-chip Market, By Application, 2019-2032 (USD Million)

23. Mexico Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

24. Europe Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

25. Europe Liver-on-a-chip Market, By Application, 2019-2032 (USD Million)

26. Europe Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

27. Germany Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

28. Germany Liver-on-a-chip Market, By Application, 2019-2032 (USD Million)

29. Germany Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

30. France Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

31. France Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

32. France Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

33. U.K. Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

34. U.K. Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

35. U.K. Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

36. Italy Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

37. Italy Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

38. Italy Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

39. Spain Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

40. Spain Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

41. Spain Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

42. Asia Pacific Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

43. Asia Pacific Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

44. Asia Pacific Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

45. Japan Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

46. Japan Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

47. Japan Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

48. China Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

49. China Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

50. China Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

51. India Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

52. India Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

53. India Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

54. South America Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

55. South America Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

56. South America Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

57. Brazil Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

58. Brazil Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

59. Brazil Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

60. Middle East and Africa Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

61. Middle East and Africa Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

62. Middle East and Africa Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

63. UAE Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

64. UAE Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

65. UAE Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

66. South Africa Liver-on-a-chip Market, By Type, 2019-2032 (USD Million)

67. South Africa Liver-on-a-chip Market, By Application 2019-2032 (USD Million)

68. South Africa Liver-on-a-chip Market, By End User, 2019-2032 (USD Million)

List of Figures 

1. Global Liver-on-a-chip Market Segmentation

2. Global Liver-on-a-chip Market: Research Methodology

3. Market Size Estimation Methodology: Bottom-Up Approach

4. Market Size Estimation Methodology: Top-Down Approach

5. Data Triangulation

6. Porter’s Five Forces Analysis 

7. Value Chain Analysis 

8. Global Liver-on-a-chip Market Attractiveness Analysis by Type 

9. Global Liver-on-a-chip Market Attractiveness Analysis by Application 

10. Global Liver-on-a-chip Market Attractiveness Analysis by End User 

11. Global Liver-on-a-chip Market Attractiveness Analysis by Region

12. Global Liver-on-a-chip Market: Dynamics

13. Global Liver-on-a-chip Market Share by Type (2023 & 2032)

14. Global Liver-on-a-chip Market Share by Application (2023 & 2032)

15. Global Liver-on-a-chip Market Share by End User (2023 & 2032)

16. Global Liver-on-a-chip Market Share by Regions (2023 & 2032)

17. Global Liver-on-a-chip Market Share by Company (2022)

Research Methodology

Market research is a method of gathering, assessing and deducing data & information about a particular market. Market research is very crucial in these days. The techniques analyze about how a product/service can be offered to the market to its end-customers, observe the impact of that product/service based on the past customer experiences, and cater their needs and demands. Owing to the successful business ventures, accurate, relevant and thorough information is the base for all the organizations because market research report/study offers specific market related data & information about the industry growth prospects, perspective of the existing customers, and the overall market scenario prevailed in past, ongoing present and developing future. It allows the stakeholders and investors to determine the probability of a business before committing substantial resources to the venture. Market research helps in solving the marketing issues challenges that a business will most likely face.

Market research is valuable because of the following reasons:

  • Market research helps businesses strengthen a company’s position
  • Market research helps in minimizing the investment risks associated with the businesses in any industry vertical
  • Market research helps in identifying the potential threats and opportunities associated with the business industry
  • Market research aids in spotting the emerging trends and facilitates strategic planning in order to stay ahead in the competition

Our research report features both the aspects; qualitative and quantitative. Qualitative part provides insights about the market driving forces, potential opportunities, customer’s demands and requirement which in turn help the companies to come up with new strategies in order to survive in the long run competition. The quantitative segment offers the most credible information related to the industry. Based on the data gathering, we use to derive the market size and estimate their future growth prospects on the basis of global, region and country.

Our market research process involves with the four specific stages.

  • Data Collection
  • Data Synthesis
  • Market Deduction & Formulation
  • Data Screening & Validation

Data Collection: This stage of the market research process involves with the gathering and collecting of the market/industry related data from the sources. There are basically two types of research methods:

  • Primary Research: By conducting primary research, it involves with the two types of data gathering; exploratory and specific. Exploratory data is open-ended and helps us to define a particular problem involving surveys, and pilot study to the specific consumer group, knowing their needs and wants catering to the industry related product/service offering. Explanatory data gathering follows with the bit of unstructured way. Our analyst group leads the study by focusing on the key crowd, in this manner picking up bits of knowledge from them. In light of the points of view of the clients, this data is used to plan advertise techniques. In addition, showcase overviews causes us to comprehend the current scenario of the business. Specific data gathering on the hand, involves with the more structured and formal way. The primary research usually includes in telephonic conversations, E-mail collaborations and up close and personal meetings/interviews with the raw material suppliers, industrial wholesalers, and independent consultants/specialists. The interviews that we conduct offers important information on showcase size and industry development patterns. Our company likewise conducts interviews with the different business specialists so as to increase generally bits of knowledge of the business/showcase.
  • Secondary Research: The secondary research incorporates with the data gathering from the non-profit associations and organizations, for example, World bank, WHO, investor relations and their presentations, statistical databases, yearly(annual reports) reports, national government records, factual databases, websites, articles, white papers, press releases, blogs and others. From the annual report, we deduce an organization's income/revenue generation to comprehend the key product segment related to the market. We examine the organization sites and implement product mapping strategy which is significant for determining the segment revenue. In the product mapping technique, we choose and categorize the products offered by the companies catering to the industry specific market, derive the segment revenue for each of the organizations to get the market estimation. We also gather data & Information based on the supply and demand side of the value chain involved with the domain specific market. The supply side denotes the distributors, wholesalers, suppliers and the demand side denotes the end-consumers/customers of the value chain. The supply side of the market is analyzed by examining the product growth across industry in each of the region followed by its pricing analysis. The demand side is analyzed by the evaluating the penetration level and adoption rates of the product by referring to the historical/past data, examine the present usage and forecasting the future trends. 
  • Purchased Database: Our purchased data provides insights about the key market players/companies along with their financial analysis. Additionally, our data base also includes market related information. 
    • We also have the agreements with various reputed data providers, consultants and third party vendors who provide information which are not limited to:
      • Export & Import Data
      • Business Information related to trade and its statistics
      • Penetration level of a particular product/service based on geography mainly focusing on the unmet prerequisites of the customers.
  • In-house Library: Apart from these third-party sources, we have our in-house library of quantitative and qualitative data & information. Our in-house database includes market data for various industry and domains. These data are updated on regular basis as per the changing market scenario. Our library includes, internal audit reports, historic databases, archives and journal publications. Sometimes there are instances where there is no metadata or raw data available for any domain specific market. For those particular cases, we utilize our expertise to forecast and estimate the market size in order to generate comprehensive data sets. Our analyst team adopts a robust research technique in order to deduce the market size and its estimates:
  • Examining demographic along with psychographic segmentation for market evaluation
  • Analyzing the macro and micro-economic indicators for each demography
  • Evaluating the current industry trends popular in the market.

Data Synthesis: This stage includes the evaluation and assessment of all the data acquired from the primary and secondary research. It likewise includes in evaluating the information for any disparity watched while information gathering identified with the market. The data & information is gathered with consideration to the heterogeneity of sources. Scientific and statistical methods are implemented for synthesizing dissimilar information sets and provide the relevant data which is fundamental for formulating strategies. Our organization has broad involvement with information amalgamation where the information goes through different stages:

  • Information Screening: Information screening is the way toward examining information/data gathered from the sources for errors/mistakes and amending it before data integration process. The screening includes in looking at raw information, identifying and distinguishing mistakes and managing missing information. The reason for the information screening is to ensure information is effectively entered or not. Our organization utilizes objective and precise information screening grades through repetitive quality checks.
  • Data Integration: The data integration method involves with the incorporation of numerous information streams. The data streams is important so as to deliver investigate examines that give overall market scenario to the investors. These information streams originate from different research contemplates and our in house database. After the screening of the information, our analysts conduct efficient integration of the data streams, optimizing connections between integrated surveys and syndicated data sources. There are two research approaches that we follow so as to coordinate our information; top down methodology and bottom up methodology. 
    • Top-down analysis generally refers to using broad factors as a basis for decision making. The top-down approach helps in identifying the overall market scenario along with the external and internal factors effecting the market growth.
    • The bottom-up approach takes a completely different approach. Generally, the bottom-up approach focuses its analysis on micro attributes and specific characteristics of the domain specific market.

Market Formulation & Deduction: The last stage includes assigning the data & information in a suitable way in order to derive market size. Analyst reviews and domain based opinions based on holistic approach of market estimation combined with industry investigation additionally features a crucial role in this stage.

This stage includes with the finalization of the market size and numbers that we have gathered from primary and secondary research. With the data & information addition, we ensure that there is no gap in the market information. Market trend analysis is finished by our analysts by utilizing data extrapolation procedures, which give the most ideal figures to the market.

Data Validation: Validation is the most crucial step in the process. Validation & re-validation through scientifically designed technique and process that helps us finalize data-points to be used for final calculations. This stage also involves with the data triangulation process. Data triangulation generally implicates the cross validation and matching the data which has been collected from primary and secondary research methods.

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